Gene:  C4B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the basic form of complement factor 4 part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha beta and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist such that individuals may have 1 2 or 3 copies of this gene. In addition this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq Jul 2008]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: C4B, Human
complement component 4B (Chido blood group)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037421
Info:   Same primer pair as used in probe assay qHsaCEP0040144
List Price:    $125.00
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PrimePCR™ Probe Assay: C4B, Human
complement component 4B (Chido blood group)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040144
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: C4B, Human
complement component 4B (Chido blood group)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5188539
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037421; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: C4B, Human
complement component 4B (Chido blood group)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5190769
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040144; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: C4B, Human
complement component 4B (Chido blood group)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5190770
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040144; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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