Gene:  BMPR2, Human

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This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors but they require their respective type I receptors for signaling whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension both familial and fenfluramine-associated and with pulmonary venoocclusive disease. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0048442
Info:   Recommended - best efficiency; Same primer pair as used in probe assay qHsaCEP0055702
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PrimePCR™ SYBR® Green Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008240
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PrimePCR™ Probe Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055702
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5012668
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048442; exonic
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5015487
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0008240; Intron-spanning
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PrimePCR™ ddPCR™ Expression Probe Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043646
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055702; exonic
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Expression Probe Assay: BMPR2, Human
bone morphogenetic protein receptor, type II (serine/threonine kinase)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043647
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055702; exonic
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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