Gene:  BCL2L1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants which encode distinct isoforms have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: BCL2L1, Human
BCL2-like 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036793
Info:   Same primer pair as used in probe assay qHsaCEP0039517
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PrimePCR™ Probe Assay: BCL2L1, Human
BCL2-like 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039517
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PrimePCR™ ddPCR™ Copy Number Assay: BCL2L1, Human
BCL2-like 1

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000156
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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