Gene:  BCL2A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by different extracellular signals such as granulocyte-macrophage colony-stimulating factor (GM-CSF) CD40 phorbol ester and inflammatory cytokine TNF and IL-1 which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036589
Info:   Same primer pair as used in probe assay qHsaCEP0039313
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PrimePCR™ Probe Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039313
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5005785
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036589; exonic
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PrimePCR™ ddPCR™ Expression Probe Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5029882
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0039313; exonic
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Expression Probe Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5029883
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0039313; exonic
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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