Gene:  BACE1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers
Pathway Curation
Control and Reference Assays for Real-Time PCR

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases one of which is the protein encoded by this gene. The encoded protein a member of the peptidase A1 protein family is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq May 2011]

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PrimePCR™ SYBR® Green Assay: BACE1, Human
beta-site APP-cleaving enzyme 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012647
Info:   Same primer pair as used in probe assay qHsaCIP0028537
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PrimePCR™ Probe Assay: BACE1, Human
beta-site APP-cleaving enzyme 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028537
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PrimePCR™ ddPCR™ Copy Number Assay: BACE1, Human
beta-site APP-cleaving enzyme 1

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000169
Info:   68nt amplicon; exonic
 
Fluorophore:   FAM
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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