Gene:  ATP2B1, Human

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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental tissue- and cell type-specific manner suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ATP2B1, Human
ATPase, Ca++ transporting, plasma membrane 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042302
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0049565
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PrimePCR™ SYBR® Green Assay: ATP2B1, Human
ATPase, Ca++ transporting, plasma membrane 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008095
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PrimePCR™ Probe Assay: ATP2B1, Human
ATPase, Ca++ transporting, plasma membrane 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049565
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    Related pathways not available
Number Description Download
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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