Gene:  ATP1A2, Human

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The protein encoded by this gene belongs to the family of P-type cation transport ATPases and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation for sodium-coupled transport of a variety of organic and inorganic molecules and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq Oct 2008]

PrimePCR™ SYBR® Green Assay: ATP1A2, Human
ATPase, Na+/K+ transporting, alpha 2 polypeptide

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013412
Info:   Same primer pair as used in probe assay qHsaCIP0028855
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PrimePCR™ Probe Assay: ATP1A2, Human
ATPase, Na+/K+ transporting, alpha 2 polypeptide

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028855
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