Gene:  ATM, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers
Pathway Curation
Control and Reference Assays for Real-Time PCR

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus it functions as a regulator of a wide variety of downstream proteins including tumor suppressor proteins p53 and BRCA1 checkpoint kinase CHK2 checkpoint proteins RAD17 and RAD9 and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia an autosomal recessive disorder. [provided by RefSeq Aug 2010]

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PrimePCR™ SYBR® Green Assay: ATM, Human
ataxia telangiectasia mutated

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001800
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PrimePCR™ SYBR® Green Assay: ATM, Human
ataxia telangiectasia mutated

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045448
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052709
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PrimePCR™ Probe Assay: ATM, Human
ataxia telangiectasia mutated

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052709
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PrimePCR™ ddPCR™ Copy Number Assay: ATM, Human
ataxia telangiectasia mutated

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000006
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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