Gene:  AR, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain DNA-binding domain and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand the receptor dissociates from accessory proteins translocates into the nucleus dimerizes and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: AR, Human
androgen receptor

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0007155
Info:   Same primer pair as used in probe assay qHsaCIP0026366
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PrimePCR™ Probe Assay: AR, Human
androgen receptor

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026366
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PrimePCR™ ddPCR™ Copy Number Assay: AR, Human
androgen receptor

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000004
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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