Gene:  APLP2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes amyloid precursor- like protein 2 (APLP2) which is a member of the APP (amyloid precursor protein) family including APP APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin- copper- and zinc- binding domains at the N-terminus BPTI/Kunitz inhibitor and E2 domains in the middle region and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

PrimePCR™ SYBR® Green Assay: APLP2, Human
amyloid beta (A4) precursor-like protein 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012534
Info:   Same primer pair as used in probe assay qHsaCIP0028482
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PrimePCR™ Probe Assay: APLP2, Human
amyloid beta (A4) precursor-like protein 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028482
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    Related pathways not available
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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