Gene:  ANK3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility activation proliferation contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2 and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Feb 2011]

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PrimePCR™ SYBR® Green Assay: ANK3, Human
ankyrin 3, node of Ranvier (ankyrin G)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002445
Info:   Recommended - best coverage
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PrimePCR™ SYBR® Green Assay: ANK3, Human
ankyrin 3, node of Ranvier (ankyrin G)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0057382
Info:   Same primer pair as used in probe assay qHsaCEP0058487
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PrimePCR™ Probe Assay: ANK3, Human
ankyrin 3, node of Ranvier (ankyrin G)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0058487
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PrimePCR™ ddPCR™ Copy Number Assay: ANK3, Human
ankyrin 3, node of Ranvier (ankyrin G)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000215
 
Fluorophore:   FAM
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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