Gene:  ACVR1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins composed of a ligand-binding extracellular domain with cysteine-rich region a transmembrane domain and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ACVR1, Human
activin A receptor, type I

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043581
Info:   Same primer pair as used in probe assay qHsaCEP0050843
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: ACVR1, Human
activin A receptor, type I

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012283
List Price:    $174.00
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PrimePCR™ Probe Assay: ACVR1, Human
activin A receptor, type I

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050843
List Price:    $255.00
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