Gene:  ABCA4, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19 cone-rod dystrophy type 3 early-onset severe retinal dystrophy fundus flavimaculatus and macular degeneration age-related 2. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0048343
Info:   Same primer pair as used in probe assay qHsaCEP0055603
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010112
Info:   Recommended - best coverage
List Price:    $125.00
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PrimePCR™ Probe Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055603
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5012583
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048343; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5016848
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010112; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043476
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055603; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: ABCA4, Human
ATP-binding cassette, sub-family A (ABC1), member 4

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5043477
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055603; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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