
Overview

5–33 cm ID Columns

45 cm ID Columns
Foresight Pro Chromatography Columns are good manufacturing practice (GMP) ready columns specifically designed to be used for all biopharmaceutical manufacturing applications. The columns have a sanitary design with minimal dead space and effective cleanability, and connections to pumping systems are made via standard 3/4" Tri-Clamp Fittings. CHT prepacked columns are available in a range of column diameters and bed heights. CHT prepacked columns are shipped in 0.1 N NaOH.
Features and Benefits
- GMP ready columns — validated and ready to use
- Excellent performance — data include asymmetry, HETP, endotoxin, and bioburden
- Patented and robust column hardware design maintains CHT packed bed
- Columns maintain performance criteria after shipping and cycling
- Columns maintain performance criteria post shipping and post cycling
- All wetted parts meet USP Class VI requirements of USP <88>
- Standard Tri-Clamp connections — plug and play
- Columns are packed in a controlled ISO Class 7 cleanroom
- Range of column diameters and bed heights — 5–45 cm ID and 10 or 20 cm bed height
- Resin reference sample included with each column
- Regulatory support file available
Packing Quality
The performance of the Foresight Pro Columns was evaluated before and after International Safe Transit Association (ISTA). As shown in Figures 1 and 2 the columns maintained performance criteria indicating excellent stability during shipping. For more details see Bulletin 3291.
Figure 1: Evaluation of N/m, comparing pre- and post-ISTA tests. Pre-ISTA test (
); Post-ISTA test(
); ISTA, International Safe Transit Association; N/m, number of theoretical plates per meter.
Figure 2: Evaluation of As, comparing pre- and post-ISTA tests. Pre-ISTA test (
); Post-ISTA test(
); As, asymmetry factor; ID, inner diameter; ISTA, International Safe Transit Association.
Cycling Data
The performance of the Foresight Pro Columns was evaluated for flow stability. The columns went through a series of cycles. Figures 3 and 4 show that the columns maintained performance criteria indicating a robust packed CHT bed. For more details see Bulletin 3291.
Figure 3: Evaluation of N/m, comparing the first and tenth cycle of Foresight Pro Columns.
First cycle (); Tenth cycle (
)
Figure 4: Evaluation of As, comparing the first and tenth cycle of Foresight Pro Columns.
Pre-ISTA 2A (); Post-ISTA 2A(
)
Non-Product Contact Material Summary
Element | Material |
---|---|
Top and bottom supporting plates | Polypropylene |
Holding bars | Polyamide or 304 stainless steel |
Wheels | Rubber wheel with stainless steel support plate and 2 locking casters |
Product Contact Material Summary
Element | Material | USP <88> Class | CFR 21 177 | Animal Origin |
---|---|---|---|---|
Column body | Glass (5 cm ID columns) | N/A | N/A | N/A |
Column body |
Acrylic (8, 10, 13, 20, 24, 33, 45 cm ID columns) |
Class VI | 177.1010 | Animal-free |
Flow distributors | Polypropylene | Class VI | 177.1520 | Animal-free |
Inlet and outlet connectors | Polypropylene | Class VI | 177.1520 | Animal-free |
Tubing connections | Reinforced elastomer tubing | Class VI | 177.2600 | Animal-free |
Tri-Clamp Gasket and O-rings | Ethylene propylene diene monomer (EPDM) | Class VI | 177.2600 | Animal-free |
Bed support screens | Polyamide
Note: The polyamide bed support screen is welded |
Class VI | 177.1500 | Animal-free |
Related Products
- CHT Ceramic Hydroxyapatite Type I Media
- CHT Ceramic Hydroxyapatite Type II Media
- CHT Ceramic Hydroxyapatite XT Media
Related Categories
Specifications
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Foresight Pro Chromatography Column, 0.2 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 5 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 0.4 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 5 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 8 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 1.0 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 8 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.8 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 10 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 1.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 10 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 1.3 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 13 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 2.7 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 13 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 3.1 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 20 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 6.3 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 20 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 4.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 24 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 9.0 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 24 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 8.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 33 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 17 L, CHT Ceramic Hydroxyapatite, Type I, 40 µm, 33 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.2 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 5 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 0.4 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 5 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 8 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 1.0 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 8 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.8 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 10 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 1.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 10 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 1.3 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 13 cm (diameter) x 10 cm (length)

Foresight Pro Column, 2.7 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 13 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 3.1 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 20 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 6.3 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 20 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 4.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 24 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 9.0 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 24 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 8.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 33 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 17 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 33 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.2 L CHT Ceramic Hydroxyapatite XT, 40 µm, 5 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 0.4 L CHT Ceramic Hydroxyapatite XT 40 µm, 5 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.5 L CHT Ceramic Hydroxyapatite XT 40 µm, 8 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 1.0 L CHT Ceramic Hydroxyapatite XT, 40 µm, 8 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 0.8 L CHT Ceramic Hydroxyapatite XT 40 µm, 10 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 1.5 L CHT Ceramic Hydroxyapatite XT, 40 µm, 10 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 1.3 L CHT Ceramic Hydroxyapatite XT, 40 µm, 13 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 2.7 L CHT Ceramic Hydroxyapatite XT, 40 µm, 13 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 3.1 L CHT Ceramic Hydroxyapatite XT, 40 µm, 20 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 6.3 L CHT Ceramic Hydroxyapatite XT, 40 µm, 20 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 4.5 L CHT Ceramic Hydroxyapatite XT, 40 µm, 24 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 9.0 L CHT Ceramic Hydroxyapatite XT, 40 µm, 24 cm (diameter) x 20 cm (length)

Foresight Pro Chromatography Column, 8.5 L CHT Ceramic Hydroxyapatite XT, 40 µm, 33 cm (diameter) x 10 cm (length)

Foresight Pro Chromatography Column, 17 L CHT Ceramic Hydroxyapatite XT, 40 µm, 33 cm (diameter) x 20 cm (length)

Foresight Pro Column, 16 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 45 cm (diameter) x 10 cm (length)

Foresight Pro Column, 32 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 45 cm (diameter) x 20 cm (length)

Foresight Pro Column, 16 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 45 cm (diameter) x 10 cm (length)

Foresight Pro Column, 32 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 45 cm (diameter) x 20 cm (length)

Foresight Pro Column, 16 L CHT Ceramic Hydroxyapatite, XT, 40 µm, 45 cm (diameter) x 10 cm (length)

Foresight Pro Column, 32 L CHT Ceramic Hydroxyapatite, XT, 40 µm, 45 cm (diameter) x 20 cm (length)