Ion Exchange Resins

Nuvia™ Ion Exchange Resins

Built on robust physical properties, high productivity, and selectivity to deliver high capacities

UNOsphere™ Anion Exchange Resins

A robust polymer, UNOsphere Q allows for high binding capacities at fast linear velocities

UNOsphere™ Cation Exchange Resins

Resin designed for high-efficiency capture of monoclonal antibodies from crude feedstreams

Macro-Prep^® Anion Exchange Resins

High-capacity chromatographic resin for analytical, semipreparative, and process-scale applications

Macro-Prep^® Cation Exchange Resins

Rigid, macroporous chromatographic resin for analytical, semipreparative, and process-scale applications

Analytical Grade Ion Exchange Resins

Purified resins sized to consistently give narrow wet mesh ranges for high resolution and reproducibility

Mixed-Mode Resins

Nuvia aPrime 4A Media

Nuvia aPrime 4A is a hydrophobic AEX resin engineered with distinctly balanced modes to optimize biomolecule interactions. It offers a wide design space and straightforward method development delivering both high purity and yield.

Nuvia cPrime Media

Nuvia cPrime mixed-mode media is designed for versatile capture and high recovery across a wide range of salt concentrations and pH in process-scale purification processes for biotherapeutic applications.

CHT Ceramic Hydroxyapatite XT Media

CHT XT Media is engineered with advanced technology, resulting in unique selectivity and robust, uniformly-sized beads with excellent pressure-flow properties. It is fine-tuned for the removal of aggregates and process impurities.

CHT Ceramic Hydroxyapatite and Crystalline Hydroxyapatite Resins

Calcium phosphate-based media offer unique selectivity and superior separation capacity

MPC Ceramic Hydroxyfluoroapatite Resin

MPC Ceramic Hydroxyfluoroapatite (Ca₁₀(PO₄)₆(OH)_1.5(F)_0.5) is a mixed-mode chromatography resin, a composite of hydroxyapatite and fluoroapatite, with unique separation properties and unmatched selectivity and resolution in the purification of biomolecules.

CFT Ceramic Fluoroapatite ResinCFT Ceramic Fluoroapatite (Ca₁₀(PO₄)₆F₂) mixed-mode media is a rigid, spherical macroporous support used in the purification of biologically active compounds.

Affinity Resins

Nuvia™ IMAC Metal Affinity Resin Nuvia IMAC (immobilized metal affinity chromatography) Resin provides an ultra-high capacity matrix over a wide range of flow rates and pH for process scale chromatography. Get reproducible separation of biomolecules free of contaminants.Protein A Resins

Chromatographic affinity resin for different IgG purification needs

Profinity IMAC ResinsProfinity IMAC resin is an affinity chromatography support for the purification of recombinant histidine (His)-tagged proteins.Profinity Exact Purification ResinProfinity eXact Affinity Purification Resin consists of a highly engineered subtilisin protease conjugated to an agarose-based matrix.Activated Affinity Media

Chromatography supports activated for spontaneous ligand immobilization using different chemistries

Ready-to-Use Affinity Media

Base matrices are available with specific ligands already coupled to capture specific molecules

Hydrophobic Interaction Chromatography Resins

Macro-Prep^® HIC Resins

Methacrylate-based beads for protein, polypeptide, enzyme, and nucleic acid purification

Bio-Beads SM-2 ResinBio-Beads SM-2 nonpolar polystyrene adsorbents are analytical-grade, neutral macroporous polymeric beads for use in hydrophobic interaction chromatography.

Size Exclusion Resins

Bio-Gel P Polyacrylamide GelBio-Gel P polyacrylamide gels, for high-resolution gel filtration, are prepared by copolymerization of acrylamide and N,N'-methylenebisacrylamide.Bio-Beads S-X ResinBio-Beads S-X Resin is composed of neutral, porous styrene divinylbenzene beads for size exclusion chromatography of lipophilic polymers and other solutes that require organic eluents.Bio-Gel A Agarose GelBio-Gel A 1.5m gel, ideal for purification of antibodies and aggregates, consists of agarose beads in which the pore size is controlled by the percentage of agarose in the gel.

Chromatography Resin Screening Tools

Foresight Prepacked Chromatography Filter Plates & Columns

Ready-to-use formats prepacked with Bio-Rad process chromatography resin to save development time

Resin Sampler PackOptimizing purification can require more than one choice of support, so Bio-Rad offers its most popular resins in a convenient sampler pack.

Process Chromatography Resources

Process Chromatography Library