Gene:  ZNF384, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a C2H2-type zinc finger protein which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1 MMP3 MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene EWSR1 on chromosome 22 or with the TAF15 gene on chromosome 17 or with the TCF3 (E2A) gene on chromosome 19 have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq Apr 2011]

PrimePCR™ SYBR® Green Assay: ZNF384, Human
zinc finger protein 384

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014793
Info:   Same primer pair as used in probe assay qHsaCIP0029556
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PrimePCR™ Probe Assay: ZNF384, Human
zinc finger protein 384

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029556
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    Related pathways not available
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