Gene:  XRCC5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6 a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: XRCC5, Human
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011752
Info:   Same primer pair as used in probe assay qHsaCIP0028164
List Price:    $142.00
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PrimePCR™ Probe Assay: XRCC5, Human
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028164
List Price:    $208.00
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