Gene:  VAV1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes cytoskeletal rearrangements and the JNK/SAPK signaling cascade leading to increased levels of viral transcription and replication. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: VAV1, Human
vav 1 guanine nucleotide exchange factor

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017111
Info:   Same primer pair as used in probe assay qHsaCIP0031030
List Price:    $142.00
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PrimePCR™ Probe Assay: VAV1, Human
vav 1 guanine nucleotide exchange factor

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031030
List Price:    $208.00
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