Gene:  USP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the family of de-ubiquitinating enzymes which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase murine double minute 2 (MDM2) MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

PrimePCR™ SYBR® Green Assay: USP2, Human
ubiquitin specific peptidase 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042065
Info:   Same primer pair as used in probe assay qHsaCEP0049328
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: USP2, Human
ubiquitin specific peptidase 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013654
Info:   Recommended - best coverage
List Price:    $146.00
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PrimePCR™ Probe Assay: USP2, Human
ubiquitin specific peptidase 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049328
List Price:    $214.00
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    Related pathways not available
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