Gene:  UPF1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: UPF1, Human
UPF1 regulator of nonsense transcripts homolog (yeast)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0020860
Info:   Same primer pair as used in probe assay qHsaCIP0032815
List Price:    $146.00
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PrimePCR™ Probe Assay: UPF1, Human
UPF1 regulator of nonsense transcripts homolog (yeast)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0032815
List Price:    $214.00
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