Gene:  TTR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes transthyretin one of the three prealbumins including alpha-1-antitrypsin transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition affecting predominantly peripheral nerve and/or the heart and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy euthyroid hyperthyroxinaemia amyloidotic vitreous opacities cardiomyopathy oculoleptomeningeal amyloidosis meningocerebrovascular amyloidosis carpal tunnel syndrome etc. [provided by RefSeq Jan 2009]

PrimePCR™ SYBR® Green Assay: TTR, Human
transthyretin

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012807
Info:   Same primer pair as used in probe assay qHsaCIP0028609
List Price:    $142.00
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PrimePCR™ Probe Assay: TTR, Human
transthyretin

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028609
List Price:    $208.00
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