Gene:  TPSG1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Tryptases comprise a family of trypsin-like serine proteases the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I beta I beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II beta II has an allelic variant beta III also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: TPSG1, Human
tryptase gamma 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003456
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: TPSG1, Human
tryptase gamma 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0057114
Info:   Same primer pair as used in probe assay qHsaCEP0058219
List Price:    $142.00
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PrimePCR™ Probe Assay: TPSG1, Human
tryptase gamma 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0058219
List Price:    $208.00
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