Gene:  TNNI2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a fast-twitch skeletal muscle protein a member of the troponin I gene family and a component of the troponin complex including troponin T troponin C and troponin I subunits. The troponin complex along with tropomyosin is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues this protein is found in corneal epithelium cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Mar 2009]

PrimePCR™ SYBR® Green Assay: TNNI2, Human
troponin I type 2 (skeletal, fast)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003827
Info:   Same primer pair as used in probe assay qHsaCEP0024838
List Price:    $146.00
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PrimePCR™ Probe Assay: TNNI2, Human
troponin I type 2 (skeletal, fast)

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024838
List Price:    $214.00
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