Gene:  TLR3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: TLR3, Human
toll-like receptor 3

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046212
Info:   Same primer pair as used in probe assay qHsaCEP0053473
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: TLR3, Human
toll-like receptor 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013344
List Price:    $142.00
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PrimePCR™ Probe Assay: TLR3, Human
toll-like receptor 3

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053473
List Price:    $208.00
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