Gene:  SSRP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a subunit of a heterodimer that along with SUPT16H forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described but its full-length nature is not known. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: SSRP1, Human
structure specific recognition protein 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0020307
Info:   Same primer pair as used in probe assay qHsaCIP0032715
List Price:    $142.00
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PrimePCR™ Probe Assay: SSRP1, Human
structure specific recognition protein 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0032715
List Price:    $208.00
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    Related pathways not available
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