Gene:  SPACA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility as well as identification of proteins for targeted contraception are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion respectively. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: SPACA1, Human
sperm acrosome associated 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043778
Info:   Same primer pair as used in probe assay qHsaCEP0051040
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: SPACA1, Human
sperm acrosome associated 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011448
List Price:    $142.00
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PrimePCR™ Probe Assay: SPACA1, Human
sperm acrosome associated 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051040
List Price:    $208.00
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    Related pathways not available
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