Gene:  SNCA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Alpha-synuclein is a member of the synuclein family which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq Mar 2009]

PrimePCR™ SYBR® Green Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003070
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PrimePCR™ SYBR® Green Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045260
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052521
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PrimePCR™ Probe Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052521
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