Gene:  SMG7, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists in part of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq Aug 2011]

PrimePCR™ SYBR® Green Assay: SMG7, Human
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0033972
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PrimePCR™ SYBR® Green Assay: SMG7, Human
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043694
Info:   Recommended - best efficiency; Same primer pair as used in probe assay qHsaCEP0050956
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PrimePCR™ Probe Assay: SMG7, Human
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050956
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