Gene:  SMAD7, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF-beta receptor type-1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jun 2010]

PrimePCR™ SYBR® Green Assay: SMAD7, Human
SMAD family member 7

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042880
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0050142
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: SMAD7, Human
SMAD family member 7

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011150
List Price:    $142.00
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PrimePCR™ Probe Assay: SMAD7, Human
SMAD family member 7

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050142
List Price:    $208.00
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