Gene:  SCN11A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits such as SCN11A mediate voltage-dependent gating and conductance while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM Apr 2004]

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PrimePCR™ SYBR® Green Assay: SCN11A, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0016322
Info:   Same primer pair as used in probe assay qHsaCIP0030516
List Price:    $138.00
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PrimePCR™ Probe Assay: SCN11A, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030516
List Price:    $202.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SCN11A, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5021569
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016322; Intron-spanning
List Price:    $138.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SCN11A, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5054320
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030516; Intron-spanning
 
Fluorophore:   FAM
List Price:    $207.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SCN11A, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5054321
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030516; Intron-spanning
 
Fluorophore:   HEX
List Price:    $207.00
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PrimePCR™ ddPCR™ Mutation Assay:SCN11A p.K303N, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2502120
Info:   72nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:SCN11A WT for p.K303N, Human
sodium channel, voltage-gated, type XI, alpha subunit

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2502121
Info:   72nt amplicon; crosses exon-intron junction; in silico
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