Gene:  RP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein another retinal-specific protein play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Transcript variants resulted from an alternative promoter and alternative splicings have been found which overlap the current reference sequence and has several exons upstream and downstream of the current reference sequence. However the biological validity and full-length nature of some variants cannot be determined at this time.[provided by RefSeq Sep 2010]

PrimePCR™ SYBR® Green Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042998
Info:   Same primer pair as used in probe assay qHsaCEP0050260
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017951
List Price:    $146.00
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PrimePCR™ Probe Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050260
List Price:    $214.00
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