Gene:  RANGAP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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RanGAP1 is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN but not of RAS by over 1000-fold. RanGAP1 is the immediate antagonist of RCC1 a regulator molecule that keeps RAN in the active GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins but is 88% identical to Fug1 the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: RANGAP1, Human
Ran GTPase activating protein 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009302
Info:   Same primer pair as used in probe assay qHsaCIP0027137
List Price:    $146.00
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PrimePCR™ Probe Assay: RANGAP1, Human
Ran GTPase activating protein 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027137
List Price:    $214.00
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