Gene:  PTEN, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-345-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-345-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: PTEN, Human
phosphatase and tensin homolog

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036796
Info:   Same primer pair as used in probe assay qHsaCEP0039520
List Price:    $142.00
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PrimePCR™ Probe Assay: PTEN, Human
phosphatase and tensin homolog

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039520
List Price:    $208.00
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