Gene:  PSMD1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base which contains 6 ATPase subunits and 2 non-ATPase subunits and a lid which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq Jul 2010]

PrimePCR™ SYBR® Green Assay: PSMD1, Human
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047003
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0054264
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: PSMD1, Human
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017984
List Price:    $174.00
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PrimePCR™ Probe Assay: PSMD1, Human
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054264
List Price:    $255.00
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