Gene:  PRR5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2) and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq Nov 2010]

PrimePCR™ SYBR® Green Assay: PRR5, Human
proline rich 5 (renal)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0020163
Info:   Same primer pair as used in probe assay qHsaCIP0032662
List Price:    $142.00
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PrimePCR™ Probe Assay: PRR5, Human
proline rich 5 (renal)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0032662
List Price:    $208.00
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