Gene:  PLAUR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the receptor for urokinase plasminogen activator and given its role in localizing and promoting plasmin formation likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: PLAUR, Human
plasminogen activator, urokinase receptor

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017227
Info:   Same primer pair as used in probe assay qHsaCIP0031103
List Price:    $142.00
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PrimePCR™ Probe Assay: PLAUR, Human
plasminogen activator, urokinase receptor

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031103
List Price:    $208.00
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