Gene:  PION, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311) a protease with numerous substrates. PION or GSAP selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al. 2010 [PubMed 20811458]).[supplied by OMIM Nov 2010]

PrimePCR™ SYBR® Green Assay: PION, Human
pigeon homolog (Drosophila)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012228
Info:   Same primer pair as used in probe assay qHsaCIP0028349
List Price:    $459.00
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PrimePCR™ Probe Assay: PION, Human
pigeon homolog (Drosophila)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028349
List Price:    $208.00
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