Gene:  PILRA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants each encoding a distinct isoform are described. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: PILRA, Human
paired immunoglobin-like type 2 receptor alpha

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038618
Info:   Same primer pair as used in probe assay qHsaCEP0041340
List Price:    $146.00
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PrimePCR™ Probe Assay: PILRA, Human
paired immunoglobin-like type 2 receptor alpha

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041340
List Price:    $214.00
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