Gene:  PGC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq Oct 2009]

PrimePCR™ SYBR® Green Assay: PGC, Human
progastricsin (pepsinogen C)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042695
Info:   Same primer pair as used in probe assay qHsaCEP0049957
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: PGC, Human
progastricsin (pepsinogen C)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006483
Info:   Recommended - best coverage
List Price:    $146.00
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PrimePCR™ Probe Assay: PGC, Human
progastricsin (pepsinogen C)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049957
List Price:    $214.00
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    Related pathways not available
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