Gene:  PFKP, Human

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The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-16-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene which maps to chromosome 10p is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase which map to chromosomes 12q13 and 21q22 respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4 P3L and P2L2.[supplied by OMIM Mar 2008]

PrimePCR™ SYBR® Green Assay: PFKP, Human
phosphofructokinase, platelet

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0005325
List Price:    $146.00
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