Gene:  PDHA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1) dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Mar 2010]

PrimePCR™ SYBR® Green Assay: PDHA1, Human
pyruvate dehydrogenase (lipoamide) alpha 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001525
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: PDHA1, Human
pyruvate dehydrogenase (lipoamide) alpha 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044412
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0051674
List Price:    $142.00
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PrimePCR™ Probe Assay: PDHA1, Human
pyruvate dehydrogenase (lipoamide) alpha 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051674
List Price:    $208.00
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