Gene:  PDGFB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB) where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7 at sites where this gene and that for COL1A1 are located are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq Oct 2008]

PrimePCR™ SYBR® Green Assay: PDGFB, Human
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0016004
Info:   Same primer pair as used in probe assay qHsaCIP0030314
List Price:    $146.00
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PrimePCR™ Probe Assay: PDGFB, Human
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030314
List Price:    $214.00
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