Gene:  PABPN1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq Dec 2010]

PrimePCR™ SYBR® Green Assay: PABPN1, Human
poly(A) binding protein, nuclear 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037959
Info:   Same primer pair as used in probe assay qHsaCEP0040682
List Price:    $146.00
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PrimePCR™ lncRNA SYBR® Green Assay:PABPN1, Human
poly(A) binding protein, nuclear 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: lncRNA Expression
Unique Assay ID: qhsaLED0134385
Info:   Same primer pair as used in probe assay qhsaLEP0211625
List Price:    $142.00
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PrimePCR™ Probe Assay: PABPN1, Human
poly(A) binding protein, nuclear 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040682
List Price:    $214.00
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PrimePCR™ lncRNA® Probe Assay:PABPN1, Human
poly(A) binding protein, nuclear 1

Assay Type: Probe
Assay Design: exonic
Application: lncRNA Expression
Unique Assay ID: qhsaLEP0211625
Info:   Same primer pair as used in SYBR assay qhsaLED0134385
List Price:    $208.00
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    Related pathways not available
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