Gene:  OAS1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the 2-5A synthetase family essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2'5'-oligoadenylates (2-5As). These molecules activate latent RNase L which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: OAS1, Human
2',5'-oligoadenylate synthetase 1, 40/46kDa

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008921
Info:   Same primer pair as used in probe assay qHsaCIP0026992
List Price:    $142.00
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PrimePCR™ Probe Assay: OAS1, Human
2',5'-oligoadenylate synthetase 1, 40/46kDa

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026992
List Price:    $208.00
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