Gene:  NUDT1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates such as 8-oxo-dGTP 8-oxo-dATP 2-hydroxy-dATP and 2-hydroxy rATP to monophosphates thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm with some in the mitochondria suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants some of which encode distinct isoforms have been identified. Additional variants have been observed but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional longer isoform (p26) has been described. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: NUDT1, Human
nudix (nucleoside diphosphate linked moiety X)-type motif 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0038594
Info:   Same primer pair as used in probe assay qHsaCIP0041316
List Price:    $142.00
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PrimePCR™ Probe Assay: NUDT1, Human
nudix (nucleoside diphosphate linked moiety X)-type motif 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0041316
List Price:    $208.00
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