Gene:  NSD1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein containing a SET domain 2 LXXLL motifs 3 nuclear translocation signals (NLSs) 4 plant homeodomain (PHD) finger regions and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var enhancer of zeste and trithorax domain protein 1 on chromosome 5 and nucleoporin 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: NSD1, Human
nuclear receptor binding SET domain protein 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046320
Info:   Same primer pair as used in probe assay qHsaCEP0053581
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: NSD1, Human
nuclear receptor binding SET domain protein 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006715
List Price:    $142.00
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PrimePCR™ Probe Assay: NSD1, Human
nuclear receptor binding SET domain protein 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053581
List Price:    $208.00
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