Gene:  NR1I3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance such as cytochrome P450 family members. Unlike most nuclear receptors this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus where it activates or represses target gene transcription. These ligands include bilirubin a variety of foreign compounds steroid hormones and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: NR1I3, Human
nuclear receptor subfamily 1, group I, member 3

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045108
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052369
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: NR1I3, Human
nuclear receptor subfamily 1, group I, member 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010615
List Price:    $174.00
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PrimePCR™ Probe Assay: NR1I3, Human
nuclear receptor subfamily 1, group I, member 3

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052369
List Price:    $255.00
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