Gene:  NOD1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD) a centrally located nucleotide-binding domain (NBD) and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling LRRs participate in protein-protein interactions and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described but the full-length nature of these variants has not been determined. [provided by RefSeq Oct 2009]

PrimePCR™ SYBR® Green Assay: NOD1, Human
nucleotide-binding oligomerization domain containing 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0005079
Info:   Same primer pair as used in probe assay qHsaCEP0025266
List Price:    $146.00
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PrimePCR™ Probe Assay: NOD1, Human
nucleotide-binding oligomerization domain containing 1

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0025266
List Price:    $214.00
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