Gene:  NLRC4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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In C. elegans Ced4 binds and activates Ced3 an apoptotic initiator caspase via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233) NOD1/CARD4 (MIM 605980) and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain found only in mammals that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM Mar 2008]

PrimePCR™ SYBR® Green Assay: NLRC4, Human
NLR family, CARD domain containing 4

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042623
Info:   Same primer pair as used in probe assay qHsaCEP0049885
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: NLRC4, Human
NLR family, CARD domain containing 4

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017019
List Price:    $146.00
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PrimePCR™ Probe Assay: NLRC4, Human
NLR family, CARD domain containing 4

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049885
List Price:    $214.00
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