Gene:  NEDD4L, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Mar 2012]

PrimePCR™ SYBR® Green Assay: NEDD4L, Dog
Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qCfaCED0034356
List Price:    $111.00
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PrimePCR™ Probe Assay: NEDD4L, Dog
Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qCfaCEP0015046
List Price:    $214.00
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